HD Pharmacoepidemiology Resources

Pharmacoepidemiology Toolbox including hd-PS version 2

The Pharmacoepidemiology Toolbox includes several released and in-development procedures, including hd-PS version 2, fast greedy matching, n:1 nearest neighbor matching, and other resources. The Toolbox is a .zip file (approximately 3 MB) that contains a Java .jar program file, SAS and R interface programs, and documentation.

Rassen JA, Glynn RJ, Brookhart MA, Schneeweiss S. Observed performance of high-dimensional propensity score analyses of treatment effects in small samples. Am J Epidemiol; In press.

**Important note for v244 and later -- please read (.txt file)

Toolbox Download (.zip file, version 2.4.4)

Using the Pharmacoepi Toolbox in SAS documentation (.pdf file)

High-dimensional Propensity Score (hd-PS) version 1

Schneeweiss S, Rassen JR, Glynn RJ, Avorn J, Mogun H, Brookhart MA. High-dimensional propensity score adjustment in studies of treatment effects using health care claims data. Epidemiology 2009. 20:512-22. (.pdf file)

hd-PS SAS Macro, version 1 (.sas file)

hd-PS Macro instructions (.doc file)

Other Epidemiology Resources

Unmeasured confounder sensitivity analysis

Schneeweiss S. Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies of therapeutics. Pharmacoepidemiology & Drug Safety 2006 May. 15(5):291-303. (.pdf file)

Sensitivity Analysis Excel worksheet (.xls file)

Episheet

Ken Rothman's Episheet (.xls file)

For resources not listed here, please see the Brigham and Women's Hospital Division of Pharmacoepidemiology and Pharmacoeconomics download page.