Welcome.
High dimensional pharmacoepidemiology takes an empirical, data-driven approach to solving the difficult problems of pharmacoepidemiology, drug safety, and comparative effectiveness research. By making use of all the information contained in insurance claims, registries, and even electronic medical records we seek to improve the validity of non-randomized research. The self-contained algorithms that we provide can be incorporated into SAS, R, or any other monitored or automated system. Read more...
Getting started.
To start using the high dimensional pharmacoepidemiology algorithms, first register for an account, and then download the Pharmacoepidemiology Toolbox Software. From there, go to the My Studies section of the site and create a new study. Creating a study lets you define study-wide variables, which you can then use to create high dimensional analyses. You can keep the analyses private, or upload aggregate results (similar to a detailed Table 1) to share with other users.
Funding.
This web page is funded by the National Library of Medicine (R01-LM010213), the National Center for Research Resources (RC1-RR-028231) and the National Heart Lung and Blood Institute (RC4 HL106376). The funding institutions are not responsible for its contents.

The site is developed and maintained by researchers at the Division of Pharmacoepidemiology and Pharmacoeconomics at the Brigham and Women's Hospital, Harvard Medical School. The site is non-profit, and the resources here are free to use for academia, government, industry, and others.